Shirdi Sai-man makea life in test tubes!!!

After lecturing and studying about the Human genome and attended the sessions my mind was reluctant to go into any other thing...So fascinating the life and science’s.I happen to read The Book”DNA The secret of life” by james D.Watson with Andrew Berry in that book under the chapter playing god: Customised DNA molecules....I happen to read an interesting thing as follows..
“Aurther kornberg was the first to“make life” in a test tube. In 1950’s as we have seen, he discovered DNA polymerase, the enzyme that replicates DNA though the formation of a complementary copy from an unzipped “parent” strand. Later he would work with the pair of viral DNA, he was ultimately able to induce the application of all the virus’s 5300 base pairs of DNA but the product was not alive. Though identical in DNA sequence to it’s parent, it was biologically inert. Something was missing. The missing ingredient would remain a mystery till 1967.When Martin Gellert at the national Institute of health and Bob Lehmann at standford simultaneously identified it. This enzyme as “ligase” Ligase made it possible to Glue the ends of the DNA molecules together...
Kornberg could replicate the viral DNA using DNA polymerase and by adding ligase, join the two ends together so that the entire molecule formed a continuous loop, just as it did in the original virus, this artificial viral DNA behaved like a original one as exactly, the virus normally multiplies in E.Coli and kornbergs test-tube DNA did that. using just a couple of enzymes, some basic chemical ingredients, and viral DNA from which to make the copy Koernberg had made a biologically active molecule. The media reported he had created life in a test tube...”
My.... it is now 2.30 nights I felt it is better to go to bed. Meanwhile I have totally left the night aarti about my sai unsung today
My sairam is great he will not take it otherwise He knows ultimately I am his child

Aum sairam.

Shirdi sai have you authored this book on genome? - Part II

This is a gigantic document, an immense book, a recipe of extravagant Length, and it all fits inside the microscopic nucleus of a tiny cell that fits easily upon the head of a pin. This book is a piece of digital information written in linear, one dimensional and one directional form and defined by the code that transliterates a small alphabet of signs into a large lexicon of meanings through the order of their groupings. So is the Genome.
only complication is that all English books are read from left to right, whereas some parts of the Genome read from left to right and some from right to left though never both at the same time
English books are written in words of variable length using twenty six letters, genomes are written entirely in three letter words, using only four letters, A, C, G, T which stands for (Adenine Cytosine Guanine and Thiamine)

Instead of being written on flat pages, they are written on long chains of sugar and phosphate called DNA molecules in which the bases are attached as side rungs, each chromosome is one pair of very long DNA molecules. This Genome book is a clever book because in the right condition it can both photocopy and read itself. The photocopying is known as REPLICATION. The reading is known as TRANSLATION
The messenger the RNA copy is the befriended by a microscopic machine called RIBOSOMES. These ribosome moves along the messenger translating each three letter CODON in turn into one letter of a different alphabet of twenty different amino acids. Each amino acid is attached to the last to form a chain in the same order as the CODON. Not all 64 three letter CODONS specifies an amino acid. Three signify stop CODON instead. And finally not all DNA spells out genes. Most of it is a jumble of repetitive or random sequences that is rarely or never transcribed: the so called junk DNA.
I had a cup of water in the middle of my presentation. A person came with a tray on it a bottle of mineral water. He placed it on my table and uttered sairam.....a sai devotee?
Aum Sairam